Sally doing her thing

Im referring to Dr Sally Wenzel of course. I never get tired of listening to her speak and educating others on the subject of asthma, particularly severe asthma. So here’s a full hour of Sally goodness! The audience in the video are physicians, but even if you’re not a medical person, if you’ve lived with […]

My 8th year in the SARP

Hard to believe, but this week I began my 8th year as a research subject for the Severe Asthma Research Program (SARP). This is actually the 3rd study (SARP III) in a series of 3 that started back in the early 2000s. Each had a different focus. They stopped recruiting new participants for SARP a […]

Dupilumab

3 and half years ago I wrote about the exciting news regarding a game changing drug called Dupilumab. Dr Wenzel and others believed that this drug was going to revolutionize the way certain forms of severe asthma are treated. Well, very soon now I’ll get to try it out myself! This past week I received […]

I’m phenotyped

Thanks to the efforts of the SARP researchers and the new era of severe asthma phenotyping, my particular flavor of the disease has finally been described. Drum roll please………………… It’s called “Long duration Th2 low/mast cell high with remodeling“, asthma. It probably sounds like a bunch of googly gob, but about half the people with […]

SARP ends, but the research continues

Though still in operation, the NIH funded Severe Asthma Research Program (SARP), which started 14 years ago, is now officially closed to new enrollees. Sadly, it looks like SARP will be the last large observational study of severe asthmatics, at least for the foreseeable future. The good news, is that there’s still a lot of […]

Lung Art

I thought this was so clever. A few months ago a good friend of mine from Toronto, asked me if I could she use one of the images I had of some mast cells and lung tissue that was collected from my airways during an earlier bronchoscopy. She was going to somehow use them for […]

A SARP’in we will go…….

In a few weeks I’m off to Pittsburgh again to participate in SARP III. The focus of SARP III is to study the stability of clinical and molecular phenotypes of severe Asthma. Basically they’re looking for the bio signature of certain mast cells in the serum and plasma and whether they are maintained over the […]

Asthma Phenotypes

Physician researchers at the University of Pittsburgh Asthma Institute at UPMC are now using molecular and genetic information to identify asthma phenotypes and customize therapies in order to improve patient outcomes. If you have asthma and would like to contribute to this on going research, please consider volunteering for

Dupilumab , A Game Changer ?

When I heard the news today that there’s a new drug in the pipeline for severe asthma, I about fell out of my chair. When you hear one of the world’s most respected asthma researchers proclaiming that this new drug is a “game changer”, you can’t help but feel a little more optimistic about the […]

Life after the Blog

Just a quick update on what Ive up too the last couple weeks. Lungs I’ve pretty much fully recovered from that last exacerbation and hospital stint. I think the intubation is what caused me to get so sick in the first place. An endotracheal tube is the perfect conduit for introducing bacteria and viruses deep […]

Boston or Bust!

So in just a few hours Bib# 21619 is off to the Boston area to take another stab at the mother of all foot races. Monday morning I will attempt to finish my 3rd Boston marathon in a row and my 8th full marathon since starting this incredible fitness journey 5 years ago. May not […]

Lunch with Sally

Had the great fortune of having lunch last week with one of my most favorite people in the whole world. Dr Wenzel was in town for the annual AAAAI convention in San Francisco and managed to squeeze in some private time with me in between her busy presentation schedule. Although we keep in close contact […]

I’m blessed

You know what? I might be cursed with crappy lungs, but I sure seem to be blessed with some cool and caring friends. Case in point: After spending a pretty ugly night in the local ER, I woke up the next day to find a bunch of Facebook alerts on my phone. My talented friend […]