No Thermoplasty for Steve


Ive been getting a lot of email lately from people asking me if I’m gonna have the new Bronchial Thermoplasty procedure done. The answer is No. Unfortunately, my asthma is too severe even for the thermoplasty ,which is being touted as a treatment reserved for the most severe form of asthma …go figure. Actually, I don’t have a lot of the reactive smooth muscle in my larger airways that Thermoplasty targets. Most of my airway narrowing takes place deep down in my lungs in the smaller airways, where they cant reach with this device.

Hopefully this new treatment will help a few people, but I’m not convinced that this is the magic bullet that we’ve all been waiting for. It also seems that the company’s definition of “very severe asthma”, is somewhat different than my own. Ironically, I was denied entry into the clinical trials phase of this new procedure back in 2006, because my asthma was deemed “too severe” by the study investigators.

People with very severe chronic asthma usually have a fair amount of scarring, and some have less twitchiness in their large airways. It would seem to me, that this new procedure has a better chance of success on those individuals who have mild to moderate persistent asthma, whose primary problem is spastic airways and who don’t have a lot of airway remodeling. Although in both cases, inflammation can play a significant role in asthma and its symptoms. Bronchial thermoplasty is not known to do anything to inflammation.

Even if I was a suitable candidate for the procedure, I’m not really sure I’d want to have it done. There just hasn’t been enough research on it in the real world, and any scientific proof that it actually works, is marginal at best. Now that this device is approved for use in the US, I think it would be wise to wait a while and see what the outcomes will be like.

2 Comments Post a Comment
  1. Amy, that is true, it might open up some more no drug options. Which would be good.

    Steve, your knowledge about asthma is amazing. I have to remind myself that you have had this for your whole life and I have only had it for three years, so of course you know more than me.

    The last asthma attack that landed me in the hospital, back in February, left me with a permanent sort of wheeze thing. I am not sure what that means for the future. I guess it does not really matter, either my asthma will keep getting worse or it won't.

  2. Steve Gupta, M.D. says:

    The company conducted a trial, called AIR trial. The FDA approval was based on this trial. The company excluded all of the more severe asthmatics from this study. However FDA approved this device for use only in severe asthmatics!!

Leave a Reply




Today, Monday , September 6th, 2010

Symptoms: Still in the yellow zoneA combination of over-exerting myself and poor air quality are doing a number on my breathing.

Fitness:No walking today.

Other News: First long walk of the training season didn't go very well. Got over heated, had constant GI problems and leg muscles were really fatigued. Just basically, not prepared for an 11 mile walk.

FEV1:37% O2 SAT: ⇩ 94% Peak Flows:⇩ 74%

Categories

Ive managed to stay out of HERE


for

6 months
and
15 days

Approaching a record number of days that Ive been hospital -free!

I went Organic

and gave up
HFCS
83
days ago

Walked



Miles in 2010
and

Since starting this blog on 6-1-2005

Got Asthma?

Become a research volunteer
for

Dr. Sally Wenzel
is Awesome!

Communities



Upcoming Gigs


Oct 3rd 2010
Sacramento ,California


April 18th, 2011 Hopkinton,Ma

I wanna hear from you

Racewalking

Wanna learn to racewalk?
Wanna learn from the best?
Learn from my coach!

Dave Mc Govern
Official Coach for the 2008
United States
Olympic Racewalking Team

Philip, Steve , Dave


Philip Dunn, Me, Dave McGovern

Archives

Winston the Cat

Accolades

Copyright

Creative Commons License
Breathinstephen by Stephen Gaudet is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.
Based on a work at Breathinstephen.com
Permissions beyond the scope of this license may be available at Breathinstephen.com

Copyright © 2008-2010 Breathinstephen.com and Winston the Cat All rights reserved.

Passing Through

Italiano

Switch to our mobile site