I’m phenotyped

Posted on 2 CommentsPosted in Asthma, asthma phenotypes, Sally Wenzel, SARP, Severe asthma

Thanks to the efforts of the SARP researchers and the new era of severe asthma phenotyping, my particular flavor of the disease has finally been described. Drum roll please………………… It’s called “Long duration Th2 low/mast cell high with remodeling“, asthma. It probably sounds like a bunch of googly gob, but about half the people with […]

SARP ends, but the research continues

Posted on 1 CommentPosted in Asthma, asthma awareness, Sally Wenzel, SARP, Severe asthma, University of Pittsburgh Asthma Institute

Though still in operation, the NIH funded Severe Asthma Research Program (SARP), which started 14 years ago, is now officially closed to new enrollees. Sadly, it looks like SARP will be the last large observational study of severe asthmatics, at least for the foreseeable future. The good news, is that there’s still a lot of […]

A SARP’in we will go…….

Posted on 1 CommentPosted in Asthma, asthma advocacy, asthma awareness, asthma phenotypes, Asthma research, Doctor appointments, People, Places and Events, Sally Wenzel, SARP, Severe asthma

In a few weeks I’m off to Pittsburgh again to participate in SARP III. The focus of SARP III is to study the stability of clinical and molecular phenotypes of severe Asthma. Basically they’re looking for the bio signature of certain mast cells in the serum and plasma and whether they are maintained over the […]

Dupilumab , A Game Changer ?

Posted on 4 CommentsPosted in Asthma, asthma awareness, Asthma Medications, asthma phenotypes, Asthma research, Sally Wenzel, Severe asthma

When I heard the news today that there’s a new drug in the pipeline for severe asthma, I about fell out of my chair. When you hear one of the world’s most respected asthma researchers proclaiming that this new drug is a “game changer”, you can’t help but feel a little more optimistic about the […]

Lunch with Sally

Posted on 7 CommentsPosted in Asthma, asthma awareness, Asthma Education, Asthma research, People, Places and Events, Sally Wenzel, SARP

Had the great fortune of having lunch last week with one of my most favorite people in the whole world. Dr Wenzel was in town for the annual AAAAI convention in San Francisco and managed to squeeze in some private time with me in between her busy presentation schedule. Although we keep in close contact […]

Cross Country Lab-Ratting

Posted on 5 CommentsPosted in Asthma, Asthma research, Severe asthma

I just accepted an invitation to participate in a new clinical research project that studies the effects of a certain oral diabetes drug on people who have severe asthma. The technical name of the study is….. “A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma” It’s being conducted at the NIH […]

SARP podcast

Posted on 3 CommentsPosted in Air-trapping, Asthma, Asthma medical tests, Asthma research, Asthma Symptoms, People, Places and Events, SARP, Shortness of Breath

Interesting article from a 2008 SARP study, titled… “More than a Matter of Degree: Severe Asthma May Be a Different Form of the Disease”. Seems to answer a lot of questions Ive always wondered about. Dr Sorkness does a great job of explaining the basics of asthma as well as the research the SARP is […]

Im going to Pennsylvania to be studied.

Posted on 11 CommentsPosted in Asthma, Asthma medical tests, Asthma research, People, Places and Events, Pulmonary function tests

SARP for short), is a collaborative research effort involving 4 different Universities, each adding their own research specialties to the mix. The basic goal of the SARP is to determine what make “severe” asthma different than the moderate of mild forms of the disease. The information they gain by studying people like me, is added […]