I’m phenotyped

Thanks to the efforts of the SARP researchers and the new era of severe asthma phenotyping, my particular flavor of the disease has finally been described. Drum roll please………………… It’s called “Long duration Th2 low/mast cell high with remodeling“, asthma. It probably sounds like a bunch of googly gob, but about half the people with […]

A SARP’in we will go…….

In a few weeks I’m off to Pittsburgh again to participate in SARP III. The focus of SARP III is to study the stability of clinical and molecular phenotypes of severe Asthma. Basically they’re looking for the bio signature of certain mast cells in the serum and plasma and whether they are maintained over the […]

Asthma Phenotypes

Physician researchers at the University of Pittsburgh Asthma Institute at UPMC are now using molecular and genetic information to identify asthma phenotypes and customize therapies in order to improve patient outcomes. If you have asthma and would like to contribute to this on going research, please consider volunteering for

Dupilumab , A Game Changer ?

When I heard the news today that there’s a new drug in the pipeline for severe asthma, I about fell out of my chair. When you hear one of the world’s most respected asthma researchers proclaiming that this new drug is a “game changer”, you can’t help but feel a little more optimistic about the […]

Lunch with Sally

Had the great fortune of having lunch last week with one of my most favorite people in the whole world. Dr Wenzel was in town for the annual AAAAI convention in San Francisco and managed to squeeze in some private time with me in between her busy presentation schedule. Although we keep in close contact […]

Bound for Beantown

( read more) Well, after all the training, all the planning, and all the hoping like crazy that my sore foot will somehow heal in time and that my lungs won’t act up too bad, for better or worse, to finish or not, the big daddy of race weekends is finally here! Saturday night I […]

Hospital stay #97

Battle scars: 4 failed arterial line attempts and 12 failed IV attempts. I have no veins left and my radial arteries are so scarred up from previous insertions, that it’s virtually impossible to get access unless they put a central line in. Very frustrating for the doctors and very painful for me. I’d been having […]

The meeting

Before I begin, let me preface this post by saying that I haven’t made up my mind as to whether I would even want lung transplant surgery, should it ever get to that point. I wanted however, to see what some of my Pulmonologists views were on this subject, and to get a feel for […]

Off to the Burgh for the SARP

I’m a lab rat…. and proud of it ! Later today I’m off to Pittsburgh, Pennsylvania for the Sally Wenzel . She’s done so much to advance the knowledge of the severe forms of this disease. I admire her and feel like I already know her. My plane leaves at 11 pm tonight, and with […]

Closing the loop on Asthma–Sally Wenzel

Found this interesting and informative article about Dr Sally Wenzel, and why she decided to get involved in severe asthma research. It gets a little technical in the middle , but well worth the read. The more I hear about this amazing women and all of her contributions to the study of this disease, the […]

Im going to Pennsylvania to be studied.

SARP for short), is a collaborative research effort involving 4 different Universities, each adding their own research specialties to the mix. The basic goal of the SARP is to determine what make “severe” asthma different than the moderate of mild forms of the disease. The information they gain by studying people like me, is added […]